

| Каталожный номер | HW492014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-DGKG Polyclonal Antibody (HW492014) is a rabbit polyclonal antibody detecting DGKG in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human DGKG (Ile451-Gln698). | ||||||||
| Цель | DAGK3, Diglyceride kinase gamma, DAG kinase gamma, DGKG, DGK-gamma, Diacylglycerol kinase gamma | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P49619 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Diacylglycerol kinase gamma (DGKG) is a ~89 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Has no apparent specificity with regard to the acyl compositions of diacylglycerol. Specifically expressed in the cerebellum where it controls the level of diacylglycerol which in turn regulates the activity of protein kinase C gamma. Through protein kinase C gamma, indirectly regulates the dendritic development of Purkinje cells, cerebellar long term depression and ultimately cerebellar motor coordination. 1. Kai, M. et al. (1994) The Journal of biological chemistry 269, 18492-8. PMID: 8034597 | ||||||||
| Примечание | For research use only. |
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