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| カタログ番号 | HC695014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-DLG1 Polyclonal Antibody (HC695014) is a rabbit polyclonal antibody detecting Disks large homolog 1; Synapse-associated protein 97; SAP-97; SAP97; hDlg; DLG1 in ELISA, IHC, WB. Suitable for Human, Dog, Mouse, Rat, and Zebrafish.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human DLG1 (Asn214-Met410). | ||||||||
| ターゲット | Disks large homolog 1; Synapse-associated protein 97; SAP-97; SAP97; hDlg; DLG1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q12959, A0A8C0TYJ0, Q811D0, Q62696, Q5PYH5, Q5PYH6, Q62108, P31016, P78352 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Disks large homolog 1 (DLG1) is a ~100 kDa protein. Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Promotes epithelial cell layer barrier function via maintaining cell-cell adhesion. May also play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. 1. Marcello, E. et al. (2013) The Journal of clinical investigation 123, 2523-38. PMID: 23676497 | ||||||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-DLG1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: U87 cell lysate
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