

| Каталожный номер | HV751014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-DNMT3B Polyclonal Antibody (HV751014) is a rabbit polyclonal antibody detecting DNMT3B in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human DNMT3B (Met1-Ser100). | ||||||||
| Цель | M.HsaIIIB, DNA (cytosine-5)-methyltransferase 3B, Dnmt3b, DNA methyltransferase HsaIIIB, DNA MTase HsaIIIB, DNMT3B | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9UBC3 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | DNA (cytosine-5)-methyltransferase 3B (DNMT3B) is a ~95 kDa protein. Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. May preferentially methylates nucleosomal DNA within the nucleosome core region. May function as transcriptional co-repressor by associating with CBX4 and independently of DNA methylation. Seems to be involved in gene silencing. 1. van den Boogaard, ML. et al. (2016) American journal of human genetics 98, 1020-1029. PMID: 27153398 | ||||||||
| Примечание | For research use only. |
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