

| Numéro de catalogue | HV518014 | ||||||||
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| Description |
Anti-DOCK4 Polyclonal Antibody (HV518014) is a rabbit polyclonal antibody detecting DOCK4 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human DOCK4 (Met1-Pro300). | ||||||||
| Cible | DOCK4, KIAA0716, Dedicator of cytokinesis protein 4 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q8N1I0 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Dedicator of cytokinesis protein 4 (DOCK4) is a ~225 kDa protein. Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration. 1. Yajnik, V. et al. (2003) Cell 112, 673-84. PMID: 12628187 2. Yan, D. et al. (2006) Journal of molecular biology 357, 755-64. PMID: 16464467 3. Hiramoto-Yamaki, N. et al. (2010) The Journal of cell biology 190, 461-77. PMID: 20679435 | ||||||||
| Note | For research use only. |
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