

| カタログ番号 | HV518014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-DOCK4 Polyclonal Antibody (HV518014) is a rabbit polyclonal antibody detecting DOCK4 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human DOCK4 (Met1-Pro300). | ||||||||
| ターゲット | DOCK4, KIAA0716, Dedicator of cytokinesis protein 4 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q8N1I0 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Dedicator of cytokinesis protein 4 (DOCK4) is a ~225 kDa protein. Functions as a guanine nucleotide exchange factor (GEF) that promotes the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form. Involved in regulation of adherens junction between cells. Plays a role in cell migration. 1. Yajnik, V. et al. (2003) Cell 112, 673-84. PMID: 12628187 2. Yan, D. et al. (2006) Journal of molecular biology 357, 755-64. PMID: 16464467 3. Hiramoto-Yamaki, N. et al. (2010) The Journal of cell biology 190, 461-77. PMID: 20679435 | ||||||||
| 注意事項 | For research use only. |
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