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Anti-Drosophila/Fruit fly Protein scalloped Polyclonal Antibody (ZD690014)

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Número de catálogoZD690014
Descripción
Anti-Drosophila/Fruit fly Protein scalloped Polyclonal Antibody (ZD690014) is a rabbit polyclonal antibody detecting Protein scalloped. Suitable for Fruit fly.
Reactividad de especiesDrosophila melanogaster (Fruit fly)
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Drosophila/Fruit fly Protein scalloped (Trp220-Glu440).
Objetivo Protein scalloped, sd
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P30052
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Fondo

Protein scalloped is a ~49 kDa protein. Transcription factor which plays a key role in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. The Hippo/SWH signaling pathway inhibits the activity of the transcriptional complex formed by Scalloped (sd) and Yki and the target genes of this pathway include cyclin-E (cycE), diap1 and bantam. Sd promotes nuclear localization of Yki. Involved in the regulation of cell-specific gene expression during development, particularly in the differentiation of the nervous system.

Nota For research use only
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C₁ (Stock Conc.)
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Working Solution
C₂ (Working Conc.)
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Anti-Drosophila/Fruit fly Protein scalloped Polyclonal Antibody

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