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| カタログ番号 | HB374014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-DTX2 Polyclonal Antibody (HB374014) is a rabbit polyclonal antibody detecting Probable E3 ubiquitin-protein ligase DTX2; 2.3.2.27; Protein deltex-2; Deltex2; hDTX2; RING finger protein 58; RING-type E3 ubiquitin transferase DTX2; DTX2; KIAA1528; RNF58 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human DTX2 (Glu392-Gln622). | ||||||||
| ターゲット | Probable E3 ubiquitin-protein ligase DTX2; 2.3.2.27; Protein deltex-2; Deltex2; hDTX2; RING finger protein 58; RING-type E3 ubiquitin transferase DTX2; DTX2; KIAA1528; RNF58 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q86UW9, Q13670, Q8R3P2 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Probable E3 ubiquitin-protein ligase DTX2 is a ~67 kDa protein. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. | ||||||||
| 注意事項 | For research use only |
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