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| カタログ番号 | HS757014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-DUSP6 Polyclonal Antibody (HS757014) is a rabbit polyclonal antibody detecting DUSP6 in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human DUSP6 (Met1-Leu347). | ||||||||
| ターゲット | Mitogen-activated protein kinase phosphatase 3, MKP3, DUSP6, PYST1, MAP kinase phosphatase 3, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, MKP-3 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q16828 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Dual specificity protein phosphatase 6 (DUSP6) is a ~42 kDa protein. Dual specificity protein phosphatase, which mediates dephosphorylation and inactivation of MAP kinases. Has a specificity for the ERK family. Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain. 1. Groom, LA. et al. (1996) The EMBO journal 15, 3621-32. PMID: 8670865 2. Mishra, A. et al. (2017) eLife 6. PMID: 29043977 | ||||||||
| 注意事項 | For research use only. |
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