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| カタログ番号 | JN912014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-E. coli groES Polyclonal Antibody (JN912014) is a rabbit polyclonal antibody detecting groES. Suitable for strain K12.
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| 種反応性 | Escherichia coli | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant E. coli groES (Met1-Ala97). | ||||||||
| ターゲット | 10 kDa chaperonin, Chaperonin-10, Co-chaperonin GroES, Cpn10, groES, groS, mopB | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P0A6F9 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||||
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||||
| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Co-chaperonin GroES is a ~10 kDa protein. Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding, probably by preventing aggregation and by entropically destabilizing folding intermediates. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. Regulates the ATPase activity of GroEL. 1. Goloubinoff, P. et al. (1989) Nature 342, 884-9. PMID: 10532860 2. Tang, YC. et al. (2006) Cell 125, 903-14. PMID: 16751100 3. Martin, J. et al. (1991) Nature 352, 36-42. PMID: 1676490 4. Tang, YC. et al. (2008) The EMBO journal 27, 1458-68. PMID: 18418386 5. Apetri, AC. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 17351-5. PMID: 18987317 6. Chakraborty, K. et al. (2010) Cell 142, 112-22. PMID: 20603018 7. Gupta, AJ. et al. (2014) Journal of molecular biology 426, 2739-54. PMID: 24816391 8. Kusukawa, N. et al. (1989) The EMBO journal 8, 3517-21. PMID: 2573517 9. Hemmingsen, SM. et al. (1988) Nature 333, 330-4. PMID: 2897629 | ||||||||
| 注意事項 | For research use only |
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