

| Número de catálogo | HP762014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human EARS2 (Gly247-Gln496). | ||||||||
| Objetivo | KIAA1970, Glutamyl-tRNA synthetase, EARS2, Probable glutamate--tRNA ligase, mitochondrial, GluRS | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q5JPH6 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial is a ~58 kDa protein. Non-discriminating glutamyl-tRNA synthetase that catalyzes aminoacylation of both mitochondrial tRNA(Glu) and tRNA(Gln) and participates in RNA aminoacylation for mitochondrial protein translation. Attachs glutamate to tRNA(Glu) or tRNA(Gln) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) or tRNA(Gln). In vitro, cytoplasmic tRNA(Gln) is slightly glutamylated, but with low activity. 1. Nagao, A. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 16209-14. PMID: 19805282 | ||||||||
| Nota | For research use only. |
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