

| Numéro de catalogue | HP762014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human EARS2 (Gly247-Gln496). | ||||||||
| Cible | KIAA1970, Glutamyl-tRNA synthetase, EARS2, Probable glutamate--tRNA ligase, mitochondrial, GluRS | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q5JPH6 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial is a ~58 kDa protein. Non-discriminating glutamyl-tRNA synthetase that catalyzes aminoacylation of both mitochondrial tRNA(Glu) and tRNA(Gln) and participates in RNA aminoacylation for mitochondrial protein translation. Attachs glutamate to tRNA(Glu) or tRNA(Gln) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) or tRNA(Gln). In vitro, cytoplasmic tRNA(Gln) is slightly glutamylated, but with low activity. 1. Nagao, A. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 16209-14. PMID: 19805282 | ||||||||
| Note | For research use only. |
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