

| Número de catálogo | HV735014 | ||||||||
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| Descripción |
Anti-EBF1 Polyclonal Antibody (HV735014) is a rabbit polyclonal antibody detecting EBF1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Danio rerio.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human EBF1 (Asp179-Ser451). | ||||||||
| Objetivo | EBF, EBF1, OE-1, COE1, Early B-cell factor, Transcription factor COE1, O/E-1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9UH73 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Transcription factor COE1 (EBF1) is a ~64 kDa protein. Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold. 1. Yang, CY. et al. (2016) Genes & development 30, 2310-2324. PMID: 27807034 | ||||||||
| Nota | For research use only. |
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