

| Número de catálogo | VK598024 | ||||||||
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| Descripción |
Anti-EBV/HHV-4 glycoprotein L/gL Polyclonal Antibody (VK598024) is a rabbit polyclonal antibody detecting EBV/HHV-4 glycoprotein L/gL. Suitable for Epstein-Barr virus.
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| Reactividad de especies | Epstein-Barr virus (HHV-4) (Human herpesvirus 4) | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant EBV/HHV-4 glycoprotein L/gL (Asn23-Gly137). | ||||||||
| Objetivo | Envelope glycoprotein L, gL | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Pureza | >95% as determined by SDS-PAGE. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P03212 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | Envelope glycoprotein L is a ~15 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. Fusion of EBV with B-lymphocytes requires the additional receptor-binding protein gp42, which forms a complex with gH/gL. The heterodimer gH/gL targets also host EPHA2 to promote viral entry. | ||||||||
| Nota | For research use only |
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