

| Numéro de catalogue | VK598024 | ||||||||
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| Description |
Anti-EBV/HHV-4 glycoprotein L/gL Polyclonal Antibody (VK598024) is a rabbit polyclonal antibody detecting EBV/HHV-4 glycoprotein L/gL. Suitable for Epstein-Barr virus.
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| Reactivité des espèces | Epstein-Barr virus (HHV-4) (Human herpesvirus 4) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant EBV/HHV-4 glycoprotein L/gL (Asn23-Gly137). | ||||||||
| Cible | Envelope glycoprotein L, gL | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Pureté | >95% as determined by SDS-PAGE. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P03212 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Envelope glycoprotein L is a ~15 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Acts as a functional inhibitor of gH and maintains gH in an inhibited form. Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH. Fusion of EBV with B-lymphocytes requires the additional receptor-binding protein gp42, which forms a complex with gH/gL. The heterodimer gH/gL targets also host EPHA2 to promote viral entry. | ||||||||
| Note | For research use only |
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