

| Numéro de catalogue | HW402014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-EFNB2 Polyclonal Antibody (HW402014) is a rabbit polyclonal antibody detecting EFNB2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human EFNB2 (Ile28-Ala229). | ||||||||
| Cible | HTK ligand, EPH-related receptor tyrosine kinase ligand 5, LERK5, Ephrin-B2, HTK-L, EFNB2, EPLG5, HTKL, LERK-5 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P52799 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Ephrin-B2 (EFNB2) is a ~36 kDa protein. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. | ||||||||
| Note | For research use only. |
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