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| カタログ番号 | HW402014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-EFNB2 Polyclonal Antibody (HW402014) is a rabbit polyclonal antibody detecting EFNB2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human EFNB2 (Ile28-Ala229). | ||||||||
| ターゲット | HTK ligand, EPH-related receptor tyrosine kinase ligand 5, LERK5, Ephrin-B2, HTK-L, EFNB2, EPLG5, HTKL, LERK-5 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P52799 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Ephrin-B2 (EFNB2) is a ~36 kDa protein. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. | ||||||||
| 注意事項 | For research use only. |
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