

| Каталожный номер | HB046014 | ||||||||
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| Описание |
Anti-EPHA1 Polyclonal Antibody (HB046014) is a rabbit polyclonal antibody detecting EPHA1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Реактивность видов | Human, Mouse | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human EPHA1 (Tyr599-Gly842). | ||||||||
| Цель | Tyrosine-protein kinase receptor EPH, EPHT1, Erythropoietin-producing hepatoma receptor, hEpha1, EPH, EPHA1, Ephrin type-A receptor 1, EPH tyrosine kinase 1, EPH tyrosine kinase, EPHT | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P21709 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ephrin type-A receptor 1 (EPHA1) is a ~108 kDa protein. Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Also plays a role in angiogenesis and regulates cell proliferation. | ||||||||
| Примечание | For research use only. |
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