

| Numéro de catalogue | HY121014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-ERCC1 Polyclonal Antibody (HY121014) is a rabbit polyclonal antibody detecting ERCC1 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ERCC1 (Met1-Pro297). | ||||||||
| Cible | ERCC1, DNA excision repair protein ERCC-1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P07992 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | DNA excision repair protein ERCC-1 (ERCC1) is a ~32 kDa protein. Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4. | ||||||||
| Note | For research use only. |
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