

| Numéro de catalogue | HV610014 | ||||||||
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| Description |
Anti-FBLN5 Polyclonal Antibody (HV610014) is a rabbit polyclonal antibody detecting FBLN5 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human FBLN5 (Leu99-Cys205). | ||||||||
| Cible | UP50, Urine p50 protein, DANCE, Fibulin-5, Developmental arteries and neural crest EGF-like protein, Dance, FBLN5, FIBL-5 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9UBX5 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Fibulin-5 (FBLN5) is a ~50 kDa protein. Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN. Stabilizes and organizes elastic fibers in the skin, lung and vasculature. Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling. May act as an adapter that mediates the interaction between FBN1 and ELN. 1. Claus, S. et al. (2008) The Journal of investigative dermatology 128, 1442-50. PMID: 18185537 2. Nakamura, T. et al. (1999) The Journal of biological chemistry 274, 22476-83. PMID: 10428823 3. El-Hallous, E. et al. (2007) The Journal of biological chemistry 282, 8935-46. PMID: 17255108 | ||||||||
| Note | For research use only. |
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