

| Número de catálogo | HY507014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-FBP1 Polyclonal Antibody (HY507014) is a rabbit polyclonal antibody detecting FBP1 in ELISA, IHC, WB. Suitable for Human, Bovine, Ovis aries, and Pig.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human FBP1 (Met1-Gln338). | ||||||||
| Objetivo | FBPase 1, FBP1, Liver FBPase, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1, FBP, Fructose-1, 6-bisphosphatase 1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P09467 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Fructose-1,6-bisphosphatase 1 (FBP1) is a ~36 kDa protein. Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. | ||||||||
| Nota | For research use only. |
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