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| カタログ番号 | HW309024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-FDFT1 Polyclonal Antibody (HW309024) is a rabbit polyclonal antibody detecting FDFT1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human FDFT1 (Met1-Gln283). | ||||||||
| ターゲット | Squalene synthase, Farnesyl-diphosphate farnesyltransferase 1, FDFT1, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P37268 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Squalene synthase (FDFT1) is a ~48 kDa protein. Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. | ||||||||
| 注意事項 | For research use only. |
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