

| Numéro de catalogue | HV462014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-FGF13 Polyclonal Antibody (HV462014) is a rabbit polyclonal antibody detecting FGF13 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Pongo abelii, and Xenopus laevis.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human FGF13 (Gly108-Arg227). | ||||||||
| Cible | FGF13, FHF-2, Fibroblast growth factor homologous factor 2, FGF-13, Fibroblast growth factor 13, FHF2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q92913 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Fibroblast growth factor 13 (FGF13) is a ~27 kDa protein. Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. 1. Wittmack, EK. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 6765-75. PMID: 15282281 2. Fry, AE. et al. (2021) American journal of human genetics 108, 176-185. PMID: 33245860 3. Fan, X. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2220578120. PMID: 36696443 | ||||||||
| Note | For research use only. |



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