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Anti-FGF13 Polyclonal Antibody (HV462014)

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Aperçu
Numéro de catalogueHV462014
Description
Anti-FGF13 Polyclonal Antibody (HV462014) is a rabbit polyclonal antibody detecting FGF13 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Pongo abelii, and Xenopus laevis.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human FGF13 (Gly108-Arg227).
Cible FGF13, FHF-2, Fibroblast growth factor homologous factor 2, FGF-13, Fibroblast growth factor 13, FHF2
Purification Purified by antigen affinity column.
Numéro d'accès Q92913
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Fibroblast growth factor 13 (FGF13) is a ~27 kDa protein. Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling.

1. Wittmack, EK. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 6765-75. PMID: 15282281
2. Fry, AE. et al. (2021) American journal of human genetics 108, 176-185. PMID: 33245860
3. Fan, X. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2220578120. PMID: 36696443
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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