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| カタログ番号 | HB415014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-FHIT Polyclonal Antibody (HB415014) is a rabbit polyclonal antibody detecting P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein; FHIT in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human FHIT (Met1-Gln147). | ||||||||
| ターゲット | Bis(5'-adenosyl)-triphosphatase; 3.6.1.29; AP3A hydrolase; AP3Aase; Adenosine 5'-monophosphoramidase FHIT; 3.9.1.-; Adenylylsulfatase; 3.6.2.1; Adenylylsulfate-ammonia adenylyltransferase; 2.7.7.51; Diadenosine 5',5'''-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein; FHIT | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P49789, O89106, Q1KZG4, Q9JIX3 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Bis(5'-adenosyl)-triphosphatase (FHIT) is a ~16 kDa protein. Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. 1. Trapasso, F. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 1592-7. PMID: 12574506 2. Huang, K. et al. (2004) Biochemistry 43, 7637-42. PMID: 15182206 3. Barnes, LD. et al. (1996) Biochemistry 35, 11529-35. PMID: 8794732 4. Lima, CD. et al. (1997) Science (New York, N.Y.) 278, 286-90. PMID: 9323207 5. Brenner, C. et al. (1997) Protein engineering 10, 1461-3. PMID: 9543008 6. Pace, HC. et al. (1998) Proceedings of the National Academy of Sciences of the United States of America 95, 5484-9. PMID: 9576908 9. Weiske, J. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 20344-9. PMID: 18077326 | ||||||||
| 注意事項 | For research use only |
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