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| カタログ番号 | HX133014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-FKBP1A Polyclonal Antibody (HX133014) is a rabbit polyclonal antibody detecting FKBP1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human FKBP1A (Gly2-Glu108). | ||||||||
| ターゲット | PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Calstabin-1, FKBP-1A, FKBP1, FKBP-12, Rotamase, FK506-binding protein 1A, Immunophilin FKBP12, FKBP12, FKBP1A, 12 kDa FKBP, 12 kDa FK506-binding protein | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P62942 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Peptidyl-prolyl cis-trans isomerase FKBP1A is a ~11 kDa protein. Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | ||||||||
| 注意事項 | For research use only. |
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