

| Каталожный номер | HB514014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-FOXE3 Polyclonal Antibody (HB514014) is a rabbit polyclonal antibody detecting Forkhead box protein E3; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; FREAC-8; FOXE3; FKHL12; FREAC8 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human FOXE3 (Pro73-Leu161). | ||||||||
| Цель | Forkhead box protein E3; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; FREAC-8; FOXE3; FKHL12; FREAC8 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q13461, Q63250, Q9QY14 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Forkhead box protein E3 (FOXE3) is a ~33 kDa protein. Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation. Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm. Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye. 1. Wang, Y. et al. (2012) Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 250, 999-1007. PMID: 22527307 2. Islam, L. et al. (2015) Human mutation 36, 296-300. PMID: 25504734 3. Khan, SY. et al. (2016) Nature communications 7, 10953. PMID: 27218149 | ||||||||
| Примечание | For research use only |
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