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| カタログ番号 | HW672014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-FRK Polyclonal Antibody (HW672014) is a rabbit polyclonal antibody detecting FRK in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human FRK (Ile234-Phe491). | ||||||||
| ターゲット | PTK5, RAK, Tyrosine-protein kinase FRK, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5, FYN-related kinase, FRK | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P42685 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Tyrosine-protein kinase FRK is a ~58 kDa protein. Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor. | ||||||||
| 注意事項 | For research use only. |
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