

| Número de catálogo | HV168014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human FRS2 (Asn19-Ser109). | ||||||||
| Objetivo | FGFR substrate 2, FRS2, Fibroblast growth factor receptor substrate 2, FGFR-signaling adaptor SNT, Suc1-associated neurotrophic factor target 1, SNT-1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q8WU20 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Fibroblast growth factor receptor substrate 2 (FRS2) is a ~57 kDa protein. Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. | ||||||||
| Nota | For research use only. |




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