Anti-FUT2 Polyclonal Antibody (HC418014)

Name: Anti-FUT2 Polyclonal Antibody
Brand: abinScience
SKU: HC418014
Price: 168 USD
Availability: InStock

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SDS

Обзор

Каталожный номер

HC418014

Описание

Anti-FUT2 Polyclonal Antibody (HC418014) is a rabbit polyclonal antibody detecting FUT2 in ELISA, IHC, WB. Suitable for Human, Hylobates lar, Pan troglodytes, and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human FUT2 (Gln29-His343).

Цель

Fucosyltransferase 2, SE2, Se, Galactoside alpha-(1, 2)-fucosyltransferase 2, Secretor blood group alpha-2-fucosyltransferase, Alpha(1, 2)FT 2, Type 1 galactoside alpha-(1, 2)-fucosyltransferase FUT2, FUT2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, Type 2 galactoside alpha-(1, 2)-fucosyltransferase FUT2, Secretor factor, SEC2

Очистка

Purified by antigen affinity column.

Номер доступа

Q10981

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Galactoside alpha-(1,2)-fucosyltransferase 2 (FUT2) is a ~39 kDa protein. Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway.

1. Lindesmith, L. et al. (2003) Nature medicine 9, 548-53. PMID: 12692541

2. Kelly, RJ. et al. (1995) The Journal of biological chemistry 270, 4640-9. PMID: 7876235

3. Borén, T. et al. (1993) Science (New York, N.Y.) 262, 1892-5. PMID: 8018146

4. Wacklin, P. et al. (2011) PloS one 6, e20113. PMID: 21625510

5. Rausch, P. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 19030-5. PMID: 22068912

6. Wacklin, P. et al. (2014) PloS one 9, e94863. PMID: 24733310

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-FUT2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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