Please ensure Javascript is enabled for purposes of website accessibility
Contactez-nous Contactez-nous
FR
Accueil > Products > Anticorps > Anticorps Primaires

Anti-GDF5 Polyclonal Antibody (HW374014)

Fiche technique Partager le produit Copier les informations
Prix(USD) :
Spécification :
  • 50ug
  • 100ug
Nombre :
Contactez-nous

  • Aperçu

  • Images

  • Reférences

  • Fiche technique

  • SDS

Aperçu
Numéro de catalogueHW374014
Description
Anti-GDF5 Polyclonal Antibody (HW374014) is a rabbit polyclonal antibody detecting GDF5 in ELISA, IHC, WB. Suitable for Mouse and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman, Mouse
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human GDF5 (Ala382-Arg501).
Cible Growth/differentiation factor 5, BMP14, BMP-14, Radotermin, GDF-5, Bone morphogenetic protein 14, GDF5, CDMP-1, Lipopolysaccharide-associated protein 4, LAP-4, CDMP1, Cartilage-derived morphogenetic protein 1, LPS-associated protein 4
Purification Purified by antigen affinity column.
Numéro d'accès P43026
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Growth/differentiation factor 5 (GDF5) is a ~55 kDa protein. Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG. Required to prevent excessive muscle loss upon denervation.

1. Bai, X. et al. (2004) Biochemical and biophysical research communications 325, 453-60. PMID: 15530414
2. Schwaerzer, GK. et al. (2012) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27, 429-42. PMID: 21976273
3. Degenkolbe, E. et al. (2013) PLoS genetics 9, e1003846. PMID: 24098149
4. Stange, K. et al. (2014) Journal of molecular biology 426, 3221-3231. PMID: 25092592
5. Triantafilou, K. et al. (2001) Nature immunology 2, 338-45. PMID: 11276205
Note For research use only.
Images
Reférences
Fiche technique
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.

Courrier : [email protected]

Liste des distributeurs

Obtenir un devis gratuit
Anti-GDF5 Polyclonal Antibody

Accès rapide

Contactez-nous

  • +86-027-65523339

  • [email protected]

  • Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine

  • linkedin
  • Ins
  • youtube
  • youtube
Droit d'auteur © 2026 abinScience. Tous droits réservés. Tous les produits sont uniquement à usage de recherche