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Anti-GDNF Polyclonal Antibody (HW706014)

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Vista general
Número de catálogoHW706014
Descripción
Anti-GDNF Polyclonal Antibody (HW706014) is a rabbit polyclonal antibody detecting GDNF in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human GDNF (Ser78-Gly107).
Objetivo hGDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, ATF, GDNF
Purificación Purified by antigen affinity column.
Número de acceso P39905
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Glial cell line-derived neurotrophic factor (GDNF) is a ~23 kDa protein. Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest.

1. Lin, LF. et al. (1993) Science (New York, N.Y.) 260, 1130-2. PMID: 8493557
2. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012
3. Goodman, KM. et al. (2014) Cell reports 8, 1894-1904. PMID: 25242331
4. Li, J. et al. (2019) eLife 8. PMID: 31535977
5. Yan, H. et al. (2004) Developmental biology 272, 118-33. PMID: 15242795
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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