Anti-GDNF Polyclonal Antibody (HW706014)

Name: Anti-GDNF Polyclonal Antibody
Brand: abinScience
SKU: HW706014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HW706014

Description

Anti-GDNF Polyclonal Antibody (HW706014) is a rabbit polyclonal antibody detecting GDNF in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human GDNF (Ser78-Gly107).

Cible

hGDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, ATF, GDNF

Purification

Purified by antigen affinity column.

Numéro d'accès

P39905

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Glial cell line-derived neurotrophic factor (GDNF) is a ~23 kDa protein. Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest.

1. Lin, LF. et al. (1993) Science (New York, N.Y.) 260, 1130-2. PMID: 8493557

2. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012

3. Goodman, KM. et al. (2014) Cell reports 8, 1894-1904. PMID: 25242331

4. Li, J. et al. (2019) eLife 8. PMID: 31535977

5. Yan, H. et al. (2004) Developmental biology 272, 118-33. PMID: 15242795

Note

For research use only.

Images

Reférences

Fiche technique

Anti-GDNF Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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