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| カタログ番号 | HW706014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-GDNF Polyclonal Antibody (HW706014) is a rabbit polyclonal antibody detecting GDNF in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GDNF (Ser78-Gly107). | ||||||||
| ターゲット | hGDNF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, ATF, GDNF | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P39905 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glial cell line-derived neurotrophic factor (GDNF) is a ~23 kDa protein. Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Acts by binding to its coreceptor, GFRA1, leading to autophosphorylation and activation of the RET receptor. Involved in the development of the neural crest. 1. Lin, LF. et al. (1993) Science (New York, N.Y.) 260, 1130-2. PMID: 8493557 2. Cik, M. et al. (2000) The Journal of biological chemistry 275, 27505-12. PMID: 10829012 3. Goodman, KM. et al. (2014) Cell reports 8, 1894-1904. PMID: 25242331 4. Li, J. et al. (2019) eLife 8. PMID: 31535977 5. Yan, H. et al. (2004) Developmental biology 272, 118-33. PMID: 15242795 | ||||||||
| 注意事項 | For research use only. |
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