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Anti-GHSR Polyclonal Antibody (HV618014)

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Aperçu
Numéro de catalogueHV618014
Description
Anti-GHSR Polyclonal Antibody (HV618014) is a rabbit polyclonal antibody detecting GHSR in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pig.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human GHSR (Met1-Arg70).
Cible Ghrelin receptor, GHSR, GHRP, GH-releasing peptide receptor, Growth hormone secretagogue receptor type 1, GHS-R
Purification Purified by antigen affinity column.
Numéro d'accès Q92847
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Growth hormone secretagogue receptor type 1 (GHSR) is a ~41 kDa protein. G-protein-coupled receptor specific to ghrelin, an appetite-regulating peptide hormone commonly found in stomach. Upon activation, stimulates appetite and promotes growth hormone secretion. Also binds other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692, 429, MK-0677, adenosine).

1. Qin, J. et al. (2022) Nature communications 13, 300. PMID: 35027551
2. Shiimura, Y. et al. (2025) Nature structural & molecular biology 32, 531-542. PMID: 39833471
3. Smith, RG. et al. (2001) Endocrine 14, 9-14. PMID: 11322507
4. Kojima, M. et al. (1999) Nature 402, 656-60. PMID: 10604470
Note For research use only.
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Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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