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| カタログ番号 | HY371014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLI1 (Phe2-Glu234). | ||||||||
| ターゲット | Oncogene GLI, GLI, Glioma-associated oncogene, GLI1, Zinc finger protein GLI1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P08151 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Zinc finger protein GLI1 is a ~117 kDa protein. Acts as a transcriptional activator. Binds to the DNA consensus sequence 5'-GACCACCCA-3'. Regulates the transcription of specific genes during normal development. Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling. 1. Murone, M. et al. (2000) Nature cell biology 2, 310-2. PMID: 10806483 2. Lo, HW. et al. (2009) Cancer research 69, 6790-8. PMID: 19706761 3. Maloverjan, A. et al. (2010) Experimental cell research 316, 627-37. PMID: 19878745 4. Gilder, AS. et al. (2013) Biochemical and biophysical research communications 440, 431-6. PMID: 24076122 5. Zhang, Y. et al. (2013) Nature communications 4, 2608. PMID: 24217340 6. Cherry, AL. et al. (2013) Acta crystallographica. Section D, Biological crystallography 69, 2563-79. PMID: 24311597 7. Kinzler, KW. et al. (1990) Molecular and cellular biology 10, 634-42. PMID: 2105456 8. Pavletich, NP. et al. (1993) Science (New York, N.Y.) 261, 1701-7. PMID: 8378770 | ||||||||
| 注意事項 | For research use only. |
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