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| カタログ番号 | HF663014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-GLS Polyclonal Antibody (HF663014) is a rabbit polyclonal antibody detecting GLS in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLS (Ile221-Leu533). | ||||||||
| ターゲット | GLS1, Glutaminase kidney isoform, mitochondrial, KIAA0838, GLS, L-glutamine amidohydrolase, K-glutaminase | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O94925 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutaminase kidney isoform, mitochondrial (GLS) is a ~73 kDa protein. Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate, the main excitatory neurotransmitter in the brain. 1. Rumping, L. et al. (2019) Human molecular genetics 28, 96-104. PMID: 30239721 2. Rumping, L. et al. (2019) JAMA neurology 76, 342-350. PMID: 30575854 3. van Kuilenburg, ABP. et al. (2019) The New England journal of medicine 380, 1433-1441. PMID: 30970188 | ||||||||
| 注意事項 | For research use only. |
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