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Anti-GLUD1 Polyclonal Antibody (HF014014)

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Vista general
Número de catálogoHF014014
Descripción
Anti-GLUD1 Polyclonal Antibody (HF014014) is a rabbit polyclonal antibody detecting GLUD1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Hylobates lar.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human GLUD1 (Asp334-Thr556).
Objetivo GLUD1, GDH 1, Glutamate dehydrogenase 1, mitochondrial, GLUD
Purificación Purified by antigen affinity column.
Número de acceso P00367
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Glutamate dehydrogenase 1, mitochondrial (GLUD1) is a ~61 kDa protein. Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. Plays a role in insulin homeostasis. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate.

1. Plaitakis, A. et al. (2000) Journal of neurochemistry 75, 1862-9. PMID: 11032875
2. Smith, TJ. et al. (2001) Journal of molecular biology 307, 707-20. PMID: 11254391
3. Choi, MM. et al. (2005) FEBS letters 579, 4125-30. PMID: 16023112
4. Haigis, MC. et al. (2006) Cell 126, 941-54. PMID: 16959573
5. MacMullen, C. et al. (2001) The Journal of clinical endocrinology and metabolism 86, 1782-7. PMID: 11297618
6. Stanley, CA. et al. (1998) The New England journal of medicine 338, 1352-7. PMID: 9571255
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-GLUD1 Polyclonal Antibody

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