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Anti-GLUD1 Polyclonal Antibody (HF014014)

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Aperçu
Numéro de catalogueHF014014
Description
Anti-GLUD1 Polyclonal Antibody (HF014014) is a rabbit polyclonal antibody detecting GLUD1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Hylobates lar.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Human GLUD1 (Asp334-Thr556).
Cible GLUD1, GDH 1, Glutamate dehydrogenase 1, mitochondrial, GLUD
Purification Purified by antigen affinity column.
Numéro d'accès P00367
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Glutamate dehydrogenase 1, mitochondrial (GLUD1) is a ~61 kDa protein. Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. Plays a role in insulin homeostasis. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate.

1. Plaitakis, A. et al. (2000) Journal of neurochemistry 75, 1862-9. PMID: 11032875
2. Smith, TJ. et al. (2001) Journal of molecular biology 307, 707-20. PMID: 11254391
3. Choi, MM. et al. (2005) FEBS letters 579, 4125-30. PMID: 16023112
4. Haigis, MC. et al. (2006) Cell 126, 941-54. PMID: 16959573
5. MacMullen, C. et al. (2001) The Journal of clinical endocrinology and metabolism 86, 1782-7. PMID: 11297618
6. Stanley, CA. et al. (1998) The New England journal of medicine 338, 1352-7. PMID: 9571255
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-GLUD1 Polyclonal Antibody

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