

| カタログ番号 | HF014014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-GLUD1 Polyclonal Antibody (HF014014) is a rabbit polyclonal antibody detecting GLUD1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Chicken, and Hylobates lar.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GLUD1 (Asp334-Thr556). | ||||||||
| ターゲット | GLUD1, GDH 1, Glutamate dehydrogenase 1, mitochondrial, GLUD | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P00367 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutamate dehydrogenase 1, mitochondrial (GLUD1) is a ~61 kDa protein. Mitochondrial glutamate dehydrogenase that catalyzes the conversion of L-glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. Plays a role in insulin homeostasis. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. 1. Plaitakis, A. et al. (2000) Journal of neurochemistry 75, 1862-9. PMID: 11032875 2. Smith, TJ. et al. (2001) Journal of molecular biology 307, 707-20. PMID: 11254391 3. Choi, MM. et al. (2005) FEBS letters 579, 4125-30. PMID: 16023112 4. Haigis, MC. et al. (2006) Cell 126, 941-54. PMID: 16959573 5. MacMullen, C. et al. (2001) The Journal of clinical endocrinology and metabolism 86, 1782-7. PMID: 11297618 6. Stanley, CA. et al. (1998) The New England journal of medicine 338, 1352-7. PMID: 9571255 | ||||||||
| 注意事項 | For research use only. |
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