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| カタログ番号 | HB695014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-GOT1 Polyclonal Antibody (HB695014) is a rabbit polyclonal antibody detecting GOT1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Equus caballus, and Macaca fascicularis.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GOT1 (Met1-Gln413). | ||||||||
| ターゲット | GOT1, Cysteine aminotransferase, cytoplasmic, Aspartate aminotransferase, cytoplasmic, Glutamate oxaloacetate transaminase 1, Cysteine transaminase, cytoplasmic, Transaminase A, cAspAT, cCAT | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P17174 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Aspartate aminotransferase, cytoplasmic (GOT1) is a ~46 kDa protein. Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. 1. Shen, H. et al. (2011) Journal of human genetics 56, 801-5. PMID: 21900944 2. Irino, Y. et al. (2016) Scientific reports 6, 36749. PMID: 27827456 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-GOT1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Mouse heart lysate
Lane 3: Mouse liver lysate
Lane 4: Rat brain lysate
Lane 5: Rat heart lysate
Lane 6: Rat liver lysate
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