

| Каталожный номер | HY491014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-GPI Polyclonal Antibody (HY491014) is a rabbit polyclonal antibody detecting GPI in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
||||||||
| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human GPI (Met263-Asn475). | ||||||||
| Цель | GPI, NLK, Neuroleukin, Phosphohexose isomerase, PHI, Sperm antigen 36, Autocrine motility factor, AMF, SA-36, PGI, Glucose-6-phosphate isomerase, Phosphoglucose isomerase | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P06744 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
||||||||
| Информация об использовании продукта |
| ||||||||
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Glucose-6-phosphate isomerase (GPI) is a ~63 kDa protein. Isomerase that catalyzes the conversion of alpha-D-glucose-6-phosphate to beta-D-fructose-6-phosphate, the second step in glycolysis, and the reverse reaction in gluconeogenesis, within the cytoplasm. Also shows C2-epimerase activity, interconverting D-glucose-6-phosphate (G6P) and D-mannose-6-phosphate (M6P). Also displays anomerase activity, interconverting alpha and beta-anomeric forms of G6P, D-fructose-6-phosphate and M6P. In addition to its metabolic role, this enzyme functions extracellularly as a cytokine: acts as autocrine motility factor (AMF), a secreted angiogenic factor that enhances endothelial cell motility. Functions as neuroleukin, a neurotrophic factor supporting the survival of spinal and sensory neurons. 1. Mojzikova, R. et al. (2018) Blood cells, molecules & diseases 69, 23-29. PMID: 28803808 2. Funasaka, T. et al. (2001) Biochemical and biophysical research communications 285, 118-28. PMID: 11437381 3. Haga, A. et al. (2000) Biochimica et biophysica acta 1480, 235-44. PMID: 11004567 4. Faik, P. et al. (1988) Nature 332, 455-7. PMID: 3352745 | ||||||||
| Примечание | For research use only. |
Свяжитесь с нами для индивидуальных предложений, оптовых запросов и других вопросов.
Почта: [email protected]
Быстрый доступ
Свяжитесь с нами
+86-027-65523339
Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China
中文
English
한국어
日本語
Español
Français
Русский