Anti-GPR4 Polyclonal Antibody (HA696014)

Name: Anti-GPR4 Polyclonal Antibody
Brand: abinScience
SKU: HA696014
Price: 168 USD
Availability: InStock

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100ug

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Каталожный номер

HA696014

Описание

Anti-GPR4 Polyclonal Antibody (HA696014) is a rabbit polyclonal antibody detecting G-protein coupled receptor 4; G-protein coupled receptor 6C.l; GPR6C.l; GPR4 in ELISA, IHC, WB. Suitable for Human, Bovine, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human GPR4 (Ile284-Gln362).

Цель

G-protein coupled receptor 4; G-protein coupled receptor 6C.l; GPR6C.l; GPR4

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P46093, Q1JQB3, P50132

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

G-protein coupled receptor 4 (GPR4) is a ~40 kDa protein. Proton-sensing G-protein coupled receptor activated by extracellular pH, which is required to monitor pH changes and generate adaptive reactions. Activated by an optimal pH of 6.8-7.2. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors, such as adenylate cyclase. GPR4 is mainly coupled to G(s) G proteins and mediates activation of adenylate cyclase activity. May also couple with G(i), G(q) and G(12)/G(13) G proteins.

1. Ludwig, MG. et al. (2003) Nature 425, 93-8. PMID: 12955148

2. Tobo, M. et al. (2007) Cellular signalling 19, 1745-53. PMID: 17462861

3. Rowe, JB. et al. (2021) The Journal of biological chemistry 296, 100167. PMID: 33478938

4. Howard, MK. et al. (2025) Cell 188, 671-687.e20. PMID: 39753132

5. Ma, Y. et al. (2025) Nature communications 16, 605. PMID: 39799123

6. Yue, X. et al. (2025) Cell research 35, 423-436. PMID: 40211064

7. Guo, L. et al. (2025) Molecular cell 85, 1658-1673.e7. PMID: 40215959

8. Chen, LN. et al. (2025) Molecular cell 85, 1640-1657.e8. PMID: 40215960

Примечание

For research use only

Изображения

Ссылки

Даташит

Anti-GPR4 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-GPR4 Polyclonal Antibody (HA696014)

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