

| Número de catálogo | HB023014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-GRK4 Polyclonal Antibody (HB023014) is a rabbit polyclonal antibody detecting GRK4 in ELISA, IHC, WB. Suitable for Human and Rat.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human GRK4 (Arg188-Phe449). | ||||||||
| Objetivo | G protein-coupled receptor kinase 4, GPRK4, GPRK2L, ITI1, G protein-coupled receptor kinase GRK4, GRK4 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P32298 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | G protein-coupled receptor kinase 4 (GRK4) is a ~66 kDa protein. Specifically phosphorylates the activated forms of G protein-coupled receptors. GRK4-alpha can phosphorylate rhodopsin and its activity is inhibited by calmodulin; the other three isoforms do not phosphorylate rhodopsin and do not interact with calmodulin. GRK4-alpha and GRK4-gamma phosphorylate DRD3. Phosphorylates ADRB2. | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-GRK4 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
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