

| Numéro de catalogue | HB059014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-GRPR Polyclonal Antibody (HB059014) is a rabbit polyclonal antibody detecting GRPR in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human GRPR (Met1-Lys114). | ||||||||
| Cible | GRP-preferring bombesin receptor, GRP-R, GRPR, Gastrin-releasing peptide receptor | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P30550 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Gastrin-releasing peptide receptor (GRPR) is a ~43 kDa protein. Receptor for gastrin-releasing peptide (GRP). Signals via association with G proteins that activate a phosphatidylinositol-calcium second messenger system, resulting in Akt phosphorylation. Contributes to the regulation of food intake. Contributes to the perception of prurient stimuli and transmission of itch signals in the spinal cord that promote scratching behavior, but does not play a role in the perception of pain. Contributes primarily to nonhistaminergic itch sensation. 1. Corjay, MH. et al. (1991) The Journal of biological chemistry 266, 18771-9. PMID: 1655761 | ||||||||
| Note | For research use only. |
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