

| Numéro de catalogue | HW765014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-GSS Polyclonal Antibody (HW765014) is a rabbit polyclonal antibody detecting GSS in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Macaca fascicularis.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human GSS (Asp268-Val474). | ||||||||
| Cible | GSH-S, Glutathione synthase, Glutathione synthetase, GSH synthetase, GSS | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P48637 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Glutathione synthetase (GSS) is a ~52 kDa protein. Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner. Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes. Participates in ophthalmate biosynthesis in hepatocytes. 1. Gali, RR. et al. (1995) The Biochemical journal 310 ( Pt 1), 353-8. PMID: 7646467 2. Dahl, N. et al. (1997) Human molecular genetics 6, 1147-52. PMID: 9215686 3. Polekhina, G. et al. (1999) The EMBO journal 18, 3204-13. PMID: 10369661 | ||||||||
| Note | For research use only. |
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