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| カタログ番号 | HY197014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-GSTA1 Polyclonal Antibody (HY197014) is a rabbit polyclonal antibody detecting GSTA1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GSTA1 (Ala2-Phe222). | ||||||||
| ターゲット | GSTA1, GTH1, GST HA subunit 1, 13-hydroperoxyoctadecadienoate peroxidase, GSTA1-1, Glutathione S-transferase A1, Androst-5-ene-3, 17-dione isomerase, GST class-alpha member 1, GST-epsilon | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P08263 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutathione S-transferase A1 (GSTA1) is a ~25 kDa protein. Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds (Probable). Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis. Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid. 1. Bogaards, JJ. et al. (1997) Chemical research in toxicology 10, 310-7. PMID: 9084911 2. Pettersson, PL. et al. (2001) The Journal of biological chemistry 276, 11698-704. PMID: 11152686 3. Seeley, SK. et al. (2006) Biochimica et biophysica acta 1760, 1064-70. PMID: 16624487 | ||||||||
| 注意事項 | For research use only. |
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