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Anti-GSTP1 Polyclonal Antibody (HY345014)

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Vista general
Número de catálogoHY345014
Descripción
Anti-GSTP1 Polyclonal Antibody (HY345014) is a rabbit polyclonal antibody detecting GSTP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Capra hircus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human GSTP1 (Met1-Gln210).
Objetivo GSTP1-1, FAEES3, GSTP1, GST3, GST class-pi, Glutathione S-transferase P
Purificación Purified by antigen affinity column.
Número de acceso P09211
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Glutathione S-transferase P (GSTP1) is a ~23 kDa protein. Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration.

1. Kong, KH. et al. (1992) Biochemical and biophysical research communications 182, 1122-9. PMID: 1540159
2. Kong, KH. et al. (1992) Biochemical and biophysical research communications 184, 194-7. PMID: 1567427
3. Kong, KH. et al. (1993) Protein engineering 6, 93-9. PMID: 8433974
4. Bogaards, JJ. et al. (1997) Chemical research in toxicology 10, 310-7. PMID: 9084911
5. Brunnström, A. et al. (2011) Lipids 46, 69-79. PMID: 21046276
6. Zhang, W. et al. (2023) Molecular cell 83, 4352-4369.e8. PMID: 38016474
7. Sun, KH. et al. (2011) Journal of neurochemistry 118, 902-14. PMID: 21668448
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-GSTP1 Polyclonal Antibody

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