Anti-GSTP1 Polyclonal Antibody (HY345014)

Name: Anti-GSTP1 Polyclonal Antibody
Brand: abinScience
SKU: HY345014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HY345014

Description

Anti-GSTP1 Polyclonal Antibody (HY345014) is a rabbit polyclonal antibody detecting GSTP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Capra hircus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human GSTP1 (Met1-Gln210).

Cible

GSTP1-1, FAEES3, GSTP1, GST3, GST class-pi, Glutathione S-transferase P

Purification

Purified by antigen affinity column.

Numéro d'accès

P09211

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Glutathione S-transferase P (GSTP1) is a ~23 kDa protein. Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration.

1. Kong, KH. et al. (1992) Biochemical and biophysical research communications 182, 1122-9. PMID: 1540159

2. Kong, KH. et al. (1992) Biochemical and biophysical research communications 184, 194-7. PMID: 1567427

3. Kong, KH. et al. (1993) Protein engineering 6, 93-9. PMID: 8433974

4. Bogaards, JJ. et al. (1997) Chemical research in toxicology 10, 310-7. PMID: 9084911

5. Brunnström, A. et al. (2011) Lipids 46, 69-79. PMID: 21046276

6. Zhang, W. et al. (2023) Molecular cell 83, 4352-4369.e8. PMID: 38016474

7. Sun, KH. et al. (2011) Journal of neurochemistry 118, 902-14. PMID: 21668448

Note

For research use only.

Images

Reférences

Fiche technique

Anti-GSTP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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