

| カタログ番号 | HY345014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-GSTP1 Polyclonal Antibody (HY345014) is a rabbit polyclonal antibody detecting GSTP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Capra hircus.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human GSTP1 (Met1-Gln210). | ||||||||
| ターゲット | GSTP1-1, FAEES3, GSTP1, GST3, GST class-pi, Glutathione S-transferase P | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P09211 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Glutathione S-transferase P (GSTP1) is a ~23 kDa protein. Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration. 1. Kong, KH. et al. (1992) Biochemical and biophysical research communications 182, 1122-9. PMID: 1540159 2. Kong, KH. et al. (1992) Biochemical and biophysical research communications 184, 194-7. PMID: 1567427 3. Kong, KH. et al. (1993) Protein engineering 6, 93-9. PMID: 8433974 4. Bogaards, JJ. et al. (1997) Chemical research in toxicology 10, 310-7. PMID: 9084911 5. Brunnström, A. et al. (2011) Lipids 46, 69-79. PMID: 21046276 6. Zhang, W. et al. (2023) Molecular cell 83, 4352-4369.e8. PMID: 38016474 7. Sun, KH. et al. (2011) Journal of neurochemistry 118, 902-14. PMID: 21668448 | ||||||||
| 注意事項 | For research use only. |
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