Anti-GSTP1 Polyclonal Antibody (HY345014)

Name: Anti-GSTP1 Polyclonal Antibody
Brand: abinScience
SKU: HY345014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HY345014

Описание

Anti-GSTP1 Polyclonal Antibody (HY345014) is a rabbit polyclonal antibody detecting GSTP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Capra hircus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human GSTP1 (Met1-Gln210).

Цель

GSTP1-1, FAEES3, GSTP1, GST3, GST class-pi, Glutathione S-transferase P

Очистка

Purified by antigen affinity column.

Номер доступа

P09211

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Glutathione S-transferase P (GSTP1) is a ~23 kDa protein. Catalyzes conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Acts as a negative regulator of ferroptosis by mediating glutathione conjugation and detoxification of 4-hydroxynonenal (4-HNE) reactive aldehyde. Negatively regulates CDK5 activity via p25/p35 translocation to prevent neurodegeneration.

1. Kong, KH. et al. (1992) Biochemical and biophysical research communications 182, 1122-9. PMID: 1540159

2. Kong, KH. et al. (1992) Biochemical and biophysical research communications 184, 194-7. PMID: 1567427

3. Kong, KH. et al. (1993) Protein engineering 6, 93-9. PMID: 8433974

4. Bogaards, JJ. et al. (1997) Chemical research in toxicology 10, 310-7. PMID: 9084911

5. Brunnström, A. et al. (2011) Lipids 46, 69-79. PMID: 21046276

6. Zhang, W. et al. (2023) Molecular cell 83, 4352-4369.e8. PMID: 38016474

7. Sun, KH. et al. (2011) Journal of neurochemistry 118, 902-14. PMID: 21668448

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-GSTP1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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