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Anti-GUCA1A Polyclonal Antibody (HA643014)

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Vista general
Número de catálogoHA643014
Descripción
Anti-GUCA1A Polyclonal Antibody (HA643014) is a rabbit polyclonal antibody detecting Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant human GUCA1A (Met1-Gly201).
Objetivo Guanylyl cyclase-activating protein 1; GCAP 1; Guanylate cyclase activator 1A; GUCA1A; C6orf131; GCAP; GCAP1; GUCA1
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P43080, P46065, P43081
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Guanylyl cyclase-activating protein 1 (GUCA1A) is a ~22 kDa protein. Stimulates retinal guanylyl cyclase when free calcium ions concentration is low and inhibits guanylyl cyclase when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of retinal guanylyl cyclase is a key event in recovery of the dark state of rod photoreceptors following light exposure. May be involved in cone photoreceptor light response and recovery of response in bright light.

1. Jiang, L. et al. (2008) Vision research 48, 2425-32. PMID: 18706439
2. Kitiratschky, VB. et al. (2009) Human mutation 30, E782-96. PMID: 19459154
3. Marino, V. et al. (2018) Human molecular genetics 27, 4204-4217. PMID: 30184081
4. Peshenko, IV. et al. (2019) The Journal of biological chemistry 294, 3476-3488. PMID: 30622141
Nota For research use only
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-GUCA1A Polyclonal Antibody

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